一、个人简介

方玉宇，副教授，硕士研究生导师，有机化学博士，中药学博士后，比利时鲁汶大学（KU Leuven）访问学者，四川省海外高层次留学人才，主要从事基于中药活性成分的分子探针并用于疾病的“诊疗一体化”及作用靶点发现研究、荧光探针用于中药材有毒有害物质快速检测和超分子识别与自组装研究。先后主持国家自然科学基金青年科学基金项目、中国博士后科学基金面上项目、四川省科技厅应用基础研究计划项目、四川省博士后科研项目特别资助（特等资助）、四川省卫健委医学科研项目、四川省教育厅自然科学科研项目、成都中医药大学“杏林学者”学科人才等各级各类科研项目10余项，参与国家级和省部级科研项目多项。目前，在Coordin. Chem. Rev., Trends Environ. Anal. Chem., Chem. Commun., Dalton Trans., Dyes Pigments, Microchem. J.等国际知名期刊共发表论文SCI论文20余篇。参编全国高等中医药院校中药学类专业双语规划教材《有机化学》，先后获得四川省科技进步二等奖（排名第六）、成都中医药大学“最受学生喜爱教师”和第二届“本科课堂教学质量二等奖”、学院“优秀党务工作者”和青年教师教学设计大赛“二等奖”等荣誉或奖励。

二、代表性成果（可含承担项目、发表论文、论著、获奖等）

1.Dongbin Zheng, Jianjun Huang, Yuyu Fang*, Yun Deng, Cheng Peng*, Wim Dehaen*. Fluorescent Probes for Ozone-Specific Recognition: An Historical Overview and Future Perspectives. Trends Environ. Anal. Chem. 2023, e00201. (IF: 13.622)

2.Dongbin Zheng, Tingrui Zhang, Ying Huang, Hanlin Chen, Yuzhi Li*, Zhixing Cao, Yun Deng, Yuyu Fang*, Cheng Peng*. Phenoxazine-conjugated-benzoeindolium as a novel mitochondria-targeted fluorescent probe for turn-on detection of sulfur dioxide and its derivatives in vivo. Microchem. J. 2022, 175, 107192. (IF: 5.304)

3.Yuyu Fang, Fan Luo, Zhixing Cao, Cheng Peng*, Wim Dehaen*. Umbelliferone-Based Fluorescent Probe for Selective Recognition of Hydrogen Sulfide and Its Bioimaging in Living Cells and Zebrafish. Chemosensors 2022, 10, 427. (IF: 4.229, invited paper)

4.Dongbin Zheng, Tingrui Zhang, Jianjun Huang, Miao Wang, Zhixing Cao*, Ying Huang, Zhiqiang Yang, Yun Deng*, Yuyu Fang*. Indole-incorporated-benzoeindolium as a novel mitochondrial and ratiometric fluorescent probe for real-time tracking of SO₂ derivatives in vivo and herb samples. Dyes Pigments 2022, 198, 109973. (IF: 5.122)

5.Miao Wang, Ruoqi Zhang, Wim Dehaen, Yuyu Fang*, Shan Qian, Yali Ren, Fang Cheng, Yuying Guo, Chuanjie Guo, Yuzhi Li, Yun Deng, Zhixing Cao*, Cheng Peng*. Specific recognition, intracellular assay and detoxification of fluorescent curcumin derivative for copper ions. J. Hazard. Mater. 2021, 420, 126490. (IF: 14.224)

6.Yuyu Fang, Wim Dehaen*. Small-molecule-based fluorescent probes for f-block metal ions: A new frontier in chemosensors. Coordin. Chem. Rev. 2021, 427, 213524. (IF: 24.833)

7.Yuyu Fang, Yun Deng*, Wim Dehaen*. Tailoring pillararene-based receptors for specific metal ion binding: From recognition to supramolecular assembly. Coordin. Chem. Rev. 2020, 415, 213313. (IF: 24.833)

8.Yuyu Fang*, Miao Wang, Yurong Shen, Mei Zhang, Zhixing Cao, Yun Deng*. Highly sensitive and selective recognition behaviour for fluoride based on a homoditopic curcumin-difluoroboron receptor. Inorg. Chim. Acta 2020, 503, 119413. (IF: 3.118)

9.Jianjun Huang, Yuyu Fang*, Wim Dehaen*. Macrocyclic Arenes Functionalized with BODIPY: Rising Stars among Chemosensors and Smart Materials. Chemosensors 2020, 8, 51. (IF: 4.229, invited paper)

10.Yue Zhang, Yun Deng, Ningping Ji, Jiahao Zhang, Chenmeng Fan, Tieying Ding, Zhixing Cao, Yuzhi Li*, Yuyu Fang*. A rationally designed flavone-based ESIPT fluorescent chemodosimeter for highly selective recognition towards fluoride and its application in live-cell imaging. Dyes Pigments 2019, 166, 473-479. (IF: 5.122)