一、个人简介

张梅，博士，教授，博士生导师，成都中医药大学药学院中药化学系教师，四川省学术和技术带头人后备人选，四川省精品课程—《中药制剂分析》负责人。现任世界中医药学会联合会道地药材专委会常务理事，中华中医药学会中药分析分会常务委员，四川省分析测试学会色谱学委员会副主任委员。一直从事中药物质基础及中药质量控制与评价等方面的教学及科研工作，作为课题负责人及主研人员承担了国家自然科学基金及部省局级科研项目近40项，获得授权发明专利5项，作为主持人及第二主研获得四川省和成都市科技进步三等奖共3项。围绕以上研究工作在相关杂志及学术会议上公开发表及交流论文150余篇。作为主编、副主编及编委参与编写《当代药用植物典》系列专著及国家“十四·五”、“十三·五”、“十二·五”、“十一·五”、“十·五”等规划教材及教参20余部。

研究领域涉及（1）中药物质基础及作用机制研究；（2）中药质量控制及评价方法研究；（3）中药分析新方法及新技术研究；（4）中药体内药物及其代谢产物分析，等。

近年来专注于防治糖尿病视网膜病变（Diabetic retinopathy, DR）有效中药复方药效物质基础及作用机制的研究，获得5项国家自然基金项目及国家教育部、四川省科技厅等多项基金资助，在Natural Product Reports、Sensors and Actuators B: Chemical、Food Chemistry （中科院1区）、Journal of Ethnopharmacology、Microchemical Journal.、Biomedicine & Pharmacotherapy（中科院2区）等期刊上以通讯作者发表学术论文30余篇。

二、招生专业

三、代表性成果

(1) Jia Wang, Fangyong Wei, Yu Wang, Qingze Liu, Runxi He, Yuxia Huang, Kuang Wei, Xuejun Xie^*, Mei Zhang^*. Exploring the quality markers and mechanism of Bushen Huoxue Prescription in prevention and treatment of diabetic retinopathy based on Chinmedomics strategy. Journal of Ethnopharmacology. DOI: 10.1016/j.jep.2022.116131

(2) Yuxia Huang, Jia Wang, Yu Wang, Wei Kuang, Mengjun Xie^*, Mei Zhang^*.Pharmacological mechanism and clinical study of Qiming granules in treating diabetic retinopathy based on network pharmacology and literature review. Journal of Ethnopharmacology. DOI: 10.1016/j.jep.2022.115861

(3) Haiyan Yang, Kejun Li, Yanping Wang, Xin Yuan^*, Mei Zhang^*. A label-free strategy for H₂O₂ assay by chemical vapor generation-atomic fluorescence spectrometry. Microchemical Journal. DOI: 10.1016/j.microc.2022.107965

(4) Liangli Li, Maohua Yang, Mei Zhang^*, Mingyan Jia^*. Inkjet-printed colorimetric sensor array for the rapid identifcation of adulterated Fritillariae cirrhosae bulbus. Sensors & Actuators: B. Chemical. DOI: 10.1016/j.snb.2022.132210

(5) Lulin Peng, Maohua Yang, Mei Zhang^*, Mingyan Jia^*. A ratiometric fluorescent sensor based on carbon dots for rapid determination of bisulfte in sugar. Food Chemistry. DOI: 10.1016/j.foodchem.2022.133265.

(6) Yueting Yu, Ziyu Zhu, Mengjun Xie, Liping Deng, Xuejun Xie^*, Mei Zhang^*. Investigation on the Q-markers of Bushen Huoxue Prescriptions for DR treatment based on chemometric methods and spectrum-effect relationship. Journal of Ethnopharmacology. DOI: 10.1016/j.jep.2021.114800

(7) Chen Yang, Lan Lu, Li Liao, Bin Zhang, Min Zeng, Kun Zou, Xia Liu, Mei Zhang^*. Establishment of GC–MS method for the determination of Pseudomonas aeruginosa biofilm and its application in metabolite enrichment analysis. Journal of Chromatography B. DOI: 10.1016/j.jchromb. 2021.122839

(8) Kejun Li, Haiyan Yang, Xin Yuan^*, Mei Zhang^*. A novel and indirect method for L-cysteine detection in traditional Chinese medicines by chemical vapor generation-atomic fluorescence spectrometry. Microchemical Journal. DOI: 10.1016/j.microc.2021.106891.

(9) Miao Zeng, Longkai Qi, Yinrui Guo, Xiangxiang Zhu, Xiaocui Tang, Tianqiao Yong, Yizhen Xie, Qingping Wu, Mei Zhang^*and Diling Chen^*.Long-Term Administration of Triterpenoids From Ganoderma lucidum Mitigates Age-Associated Brain Physiological Decline via Regulating Sphingolipid Metabolism and Enhancing Autophagy in Mice. Frontiers in Aging Neuroscience. DOI: 10.3389/fnagi.2021.628860

(10) Mengjun Xie, Yueting Yu, Ziyu Zhu, Liping Deng, Bo Ren^*, Mei Zhang^*. Simultaneous determination of six main components in BushenHuoxue prescription by HPLC-CAD. Journal of Pharmaceutical and Biomedical Analysis. DOI: 10.1016/j.jpba.2021.114087

(11) Dan Cai, JiaoJiao Zhang, ZeHong Wu, FuYing Qin, YongMing Yan, Mei Zhang^*, YongXian Cheng^*. Lucidumones B-H, racemic meroterpenoids that inhibit tumor cell migration from Ganoderma lucidum. Bioorganic Chemistry. DOI: 10.1016/j.bioorg.2021.104774

(12) Kejun Li, Haiyan Yang, Xin Yuan^*, Mei Zhang^*. Recent developments of heavy metals detection in traditional Chinese medicine by atomic spectrometry. Microchemical Journal. DOI: 10.1016/j.microc.2020.105726

(13) Mengjun Xie, Liping Deng , Yueting Yu , Xuejun Xie^,*, Mei Zhang^*. The effects of Bushen Yiqi Huoxue prescription and its disassembled prescriptions on a diabetic retinopathy model in Sprague Dawley rats. Biomedicine & Pharmacotherapy. DOI: 10.1016/j.biopha.2020.110920

(14) Mingyan Jia^*，Yixuan Pan，Jianbo Zhou，Mei Zhang^*. Identification of Chinese teas by a colorimetric sensor array based on tea polyphenol induced indicator displacement assay. Food Chemistry. DOI: 10.1016/j.foodchem.2020.127566

(15) Yang Li, Yanru Zhang, Bo Cao, Fengqin Zhang, Ming Niu, Xue Bai, Mei Zhang^*, Haizhu Zhang^*. Screening for the antiplatelet aggregation quality markers of Salvia yunnanensis based on an integrated approach. Journal of Pharmaceutical and Biomedical Analysis. DOI：10.1016/j.jpba.2020.113383