个人简介

       严铸云，博士、教授，硕士和博士研究生导师；四川省学术和技术带头人，四川省中医药管理局学术和技术带头人，第四批全国老中医药专家学术经验继承人；兼任全国药用植物学课程联盟副理事长，中国植物学会药用植物与植物药专业委员会委员，全国中药种子（苗）标准化委员会委员，中国生态学会中药资源生态专业委员会委员，四川省药学会中药与天然药专业委员会委员，中国自然资源学会天然药物资源专业委员会委员，中国植物学会四川分会理事、副秘书长；

研究方向

       道地药材品质形成与调控机制研究、中药资源品质评价研究；先后主持国家支撑计划、国家重点研发计划和国家自然科学基金等课题20余项；倡导基于中药性效的品质控制和资源开发策略，提出中药物质基础是植物与内生菌共代谢的产物，连作障碍是土壤微生态失衡应终结于生态平衡的研究思想，开启了中药微生态研究的新领域；围绕丹参、川芎、川贝母等的品质形成机制和微生态调控开展研究工作；在International Journal of Biological Macromolecules、Food Science and Technology、Frontiers in plant science、中国中药杂志等期刊发表论文200余篇，获省部级科学技术进步二等奖1项、三等奖3项，省级教学成果一等奖2项、二等奖1项，授权专利3项；出版专著和教材20余部，其中主编国家级规划教材《药用植物学》、《中药拉丁语》、《四省藏区中药材生产加工适宜技术》、《中药微生态学》等10部，副主编《中药资源专论》（研究生教材）、《中国药用植物志》、《中国民族药辞典》等9部。

代表性成果

[1] Yu Liu, Ke Wang, Zhuyun Yan, Xiaofeng Shen, Xinjie Yang. Prediction of active ingredients in Salvia miltiorrhiza Bunge. based on soil elements and artificial neural network[J].PeerJ, 2022: e12726  

[2] Ke Wang, Zhuyun Yan, Yuntong Ma, Bo Li, Wei Wang, Luming Qi, Hongmei Jia, Na Li, Zhun Wang. A Mathematical Model for Characterizing the Biomass and the Physiological/Biochemical Indicators of Salvia miltiorrhiza Based on Growth-Defense Tradeoff[J].Frontiers in plant science,2022:      e793574

[3] Yu Liu, Maoling Tan, Wenjing Zhu, Yanan Cao, Lianxin Peng, Zhuyun Yan, Gang Zhao.In Vitro Effects of Tartary Buckwheat-Derived Nanovesicles on Gut Microbiota[J].     Journal of agricultural and food chemistry, 2022: 2616-2629             

[4] Hongyang Lv, Xiaorui Zhang, Yuanyuan Ren, Yijia Zeng, Qian Fang, Qinwen Fu, Dongmei He, Zhuyun Yan. Title The Use of GC‐MS and Network Pharmacology to Analyze the Material Basis and Mechanism of Ligusticum chuanxiong Hort. in Treating Chronic Cerebral Circulation Insufficiency[J].Chemistry Select,2022:1-13            

[5] Zhendong Yao, Yanan Cao, Lianxin Peng, Zhuyun Yan, Gang Zhao. Coarse Cereals and Legume Grains Exert Beneficial Effects through Their Interaction with Gut Microbiota: A Review[J]. Journal of agricultural and food chemistry, 2021:861-877       

[6] Jingwen Zhou, Rui Liu, Min Shuai, Zhuyun Yan, Xin Chen. Comparative transcriptome analyses of different Salvia miltiorrhiza varieties during the accumulation of tanshinones [J].Peer J,2021:e12300

[7] Bujin Ma, Jing Ma, Bo Li, Qian Tao, Jiaxia Gan, Zhuyun Yan. Effects of different harvesting times and processing methods on the quality of cultivated Fritillaria cirrhosa D. Don[J].Food science & nutrition, 2021,6:2853-2861           

[8] Yanhong Wu, Hai Wang, Min Liu, Bo Li, Xin Chen,Yuntong Ma, Zhuyun Yan. Effects of Native Arbuscular Mycorrhizae Isolated on Root Biomass and Secondary Metabolites of Salvia miltiorrhiza Bge.[J]. Frontiers in plant science,2021:617892            

[9] Lei Kang, Dongmei He, Hai Wang, Guiqi Han, Hongyang Lv, Wanting Xiao, Zhanling Zhang, Zhuyun Yan, Luqi Huang. “Breeding on Mountains" Resulted in the Reorganization of Endophytic Fungi in Asexually Propagated Plants (Ligusticum chuanxiong Hort.)[J].Frontiers in plant science, 2021:740456    

[10] Yurui Wu, Cuibai Li, Yanhong Wu, Lan Li, Wenbo Li, Bujin Ma, Zhuyun Yan. Diversity and function of culturable actinobacteria in the root-associated of Salvia miltiorrhiza Bunge[J].Peer J,2021:e11749  

[11] Wenjing Zhu, Yu Liu, Yanan Cao, Lianxin Peng, Zhuyun Yan, Gang Zhao. Insights into Health-Promoting Effects of Plant MicroRNAs: A Review[J].Journal of agricultural and food chemistry,2021:4372–14386 

[12] Baojie Zhu, Zhuyun Yan, Liang Hong, Shaoping Li, Jing Zhao. Quality evaluation of Salvia miltiorrhiza from different geographical origins in China based on qualitative and quantitative saccharide mapping and chemometrics[J].Journal of pharmaceutical and biomedical analysis,2020:113583

[13] Furong Zhong, Ling Huang, Luming Qi, Yuntong Ma, zhuyun Yan. Full-length Transcriptome Analysis of Coptis Deltoidea and Identification of Putative Genes Involved in Benzylisoquinoline Alkaloids Biosynthesis Based on Combined Sequencing Platforms[J].Plant molecular biology,2020: 4/5:477-499        

[14] Yanhong Wu, Yurui Wu, Bo Li, Zhuyun Yan. Cryptotanshinone: A review of its pharmacology activities and molecular mechanisms[J]. Fitoterapia,2020:104633            

[15] Luming Qi, Furong Zhong, Yang Chen, Shengnan Mao, Zhuyun Yan, Yuntong Ma. An integrated spectroscopic strategy to trace the geographical origins of emblic medicines: Application for the quality assessment of natural  medicines[J].Journal of Pharmaceutical Analysis,2020,(4):356-364

[16] Ting Chen, Furong Zhong, Cheng Yao, Jia Chen, Yiqing Xiang, Jijing Dong, Zhuyun Yan, Yuntong Ma. A Systematic Review on Traditional Uses, Sources, Phytochemistry, Pharmacology, Pharmacokinetics, and Toxicity of Fritillariae Cirrhosae Bulbus[J].Evidence-based complementary and alternative medicine : eCAM, 2020:1536534

[17] Lianxin Peng, Qu Zhang, Yanhong Zhang, Zhendong Yao, Panpan Song, Lijuan Wei, Gang Zhao, Zhuyun Yan. Effect of tartary buckwheat, rutin, and quercetin on lipid metabolism in rats during high dietary fat intake[J].Food Science & Nutrition,2020,(1):199-213         

[18] Kui Zhao, Bo Li, Dongmei He, Can Zhao, Zhengjun Shi, Binbin Dong, Duo Pan, Rahul Rangrao Patil, Zhuyun Yan, Zhanhu Guo. Chemical characteristic and bioactivity of hemicellulose-based polysaccharides isolated from Salvia miltiorrhiza[J]. International Journal of Biological Macromolecules, 2020, Part B: 2475-2483        

[19] 严铸云,何冬梅,王海,展望微生态理论和技术在中药研究中的应用[J].中药与临床,2017,8(5):18-22.

[20] 严铸云,略论中药资源科学面临的现实与挑战[J].中药与临床,2012,0(6):1-5.